Sucralose (sold under the brand name Splenda) was approved by the U.S. Food and Drug Administration (FDA) in 1998 as a tabletop sweetener and for use in products such as baked goods, nonalcoholic beverages, chewing gum, frozen dairy desserts, fruit juices and gelatins.
It’s also permitted as a general-purpose sweetener for processed foods. (In the European Union, sucralose is known under the additive code E955.) The approval was given after the FDA supposedly reviewed more than 110 animal and human safety studies, but of these 110 studies, only two were done on humans, and the longest one lasted just four days.
I knew the approval of sucralose was a nearly identical mistake that the FDA made with aspartame, which is why I wrote my book, “Sweet Deception,” in 2006, despite the fact Johnson & Johnson threatened to sue me if I published it. It is certainly vindicating to see the studies confirm what I wrote about in my book over 12 years ago. And the video I made above was shot over seven years ago.
Artificial sweeteners like aspartame and sucralose may have zero calories, but your body isn’t fooled. When hit with a “sweet” taste, your body expects calories to follow, and when this doesn’t happen, it causes biochemical distortions that can result in weight gain, metabolic dysfunction and other health problems.
Sucralose Decimates Your Gut Microbiome
Different artificial sweeteners have been found to wreak havoc in a number of different ways. Aspartame, for example, has a long list of studies detailing harmful effects ranging from brain damage to preterm delivery. Sucralose, meanwhile, has been found to be particularly damaging to your gut. Research1 published in 2008 found sucralose:
- Reduces gut bacteria by 50 percent, preferentially targeting bacteria known to have important human health benefits (consuming as few as seven little Splenda packages is enough to have a detrimental effect on your microbiome)
- Increases the pH level in your intestines
- Is absorbed into and accumulates in fat tissue
In response to this study, James Turner, chairman of the national consumer education group Citizens for Health issued the following statement:2
“The report makes it clear that the artificial sweetener Splenda and its key component sucralose pose a threat to the people who consume the product. Hundreds of consumers have complained to us about side effects from using Splenda and this study … confirms that the chemicals in the little yellow package should carry a big red warning label.”
New Study Finds Sucralose Is Metabolized and Stored in Your Body
Needless to say, the industry has vehemently defended sucralose (and all other chemical sweeteners), stating that it rapidly passes unmetabolized through your body and therefore has no biological effects. Alas, recent research has punched yet another giant hole in the argument that sucralose is a biologically inert chemical, showing it is in fact metabolized and that it accumulates in fat cells.
The study3,4 in question was published in the online version of the Journal of Toxicology and Environmental Health August 21, 2018. An interview with the authors can be found on Inverse.5
Ten rats were given an average dose of 80.4 milligrams (mg) of sucralose per kilo per day (k/day) for 40 days. According to the researchers, this dosage is “within the range utilized in historical toxicology studies submitted for regulatory approval in North America, Europe and Asia.”